Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases.
Ta-Ching ChenChao-Yuan YehChao-Wen LinChung-May YangChang-Hao YangI-Hung LinPao-Yang ChenJung-Yu ChengFung-Rong HuPublished in: PloS one (2017)
Peripapillary vascular hypoperfusion was found in patients experiencing AON combined with disc swelling. These findings are unlike those for other ocular inflammatory diseases but are consistent with cerebral hypoperfusion, which is found in brain demyelinating diseases; thus, these findings may represent a new neurovascular model in this field.
Keyphrases
- cognitive impairment
- end stage renal disease
- optical coherence tomography
- optic nerve
- ejection fraction
- chronic kidney disease
- newly diagnosed
- oxidative stress
- prognostic factors
- liver failure
- subarachnoid hemorrhage
- cerebral ischemia
- multiple sclerosis
- white matter
- respiratory failure
- drug induced
- brain injury
- blood brain barrier
- extracorporeal membrane oxygenation