Immunoglobulin free light chains in severe asthma patient: Could they be a new biomarker?

Cristiano CarusoG CiascaI BaglivoR Di SantoA GasbarriniDavide Firinu Diego Bagnasco Giovanni PassalacquaM SchiappoliMarco CaminatiG W CanonicaEnrico HefflerC CrimiR IntravaiaV BasileM MarinoS ColantuonoStefano R Del Giacco

Published in: Allergy (2024)

Our findings confirmed the role of FLCs in asthma as a potential biomarker in an inflammatory disease characterized by different endotypes and phenotypes. In particular, FLC-κ and FLC-k/FLC-λ ratio could be a qualitative indicator for asthma, while FLC-λ levels could be a quantitative indicator for clinical severity parameters.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
oxidative stress
case report
high resolution
air pollution