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TGF-β1 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis.

Yen-Chin LiuHung-Tsung HsiaoJeffrey Chi-Fei WangTzu-Cheng WenShiou-Lan Chen
Published in: PloS one (2022)
TGF-β1 but not BDNF, TNF-α, or IL-8 may be an important biological indicator in the CSF of osteoarthritis patients with chronic pain.
Keyphrases
  • chronic pain
  • cerebrospinal fluid
  • rheumatoid arthritis
  • transforming growth factor
  • pain management
  • knee osteoarthritis
  • epithelial mesenchymal transition
  • stress induced