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Quantification of the misidentification of Plasmodium knowlesi as Plasmodium malariae by microscopy: an analysis of 1569 P. knowlesi cases.

Aongart MahittikornFrederick Ramirez MasangkayKwuntida Uthaisar KotepuiGiovanni De Jesus MilanezManas Kotepui
Published in: Malaria journal (2021)
Although the World Health Organization (WHO) recommends that all P. malariae-positive diagnoses made by microscopy in P. knowlesi endemic areas be reported as P. malariae/P. knowlesi malaria, the possibility of microscopists misidentifying P. knowlesi as P. malariae is a diagnostic challenge. The use of molecular techniques in cases with malariae-like Plasmodium with high parasite density as determined by microscopy could help identify human P. knowlesi cases in non-endemic countries.
Keyphrases
  • plasmodium falciparum
  • single molecule
  • high resolution
  • high speed
  • optical coherence tomography
  • high throughput
  • endothelial cells
  • mass spectrometry
  • toxoplasma gondii