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Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report.

Amanda V JensonAli Yunus RizviRebecca A ReynoldsSara Hartnett-WrightThomas J GellarStacie StapletonIgnacio Gonzalez-GomezS Hassan A AkbariMatthew D Smyth
Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2024)
Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.
Keyphrases
  • atrial fibrillation
  • subarachnoid hemorrhage
  • cerebral ischemia
  • germ cell
  • optic nerve
  • systematic review
  • mental health
  • brain injury
  • young adults