Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization.

Jianling ZouYing LiuJingyuan WangZhentao LiuZhihao LuZuhua ChenZhongwu LiBin DongWenwen HuangYanyan LiJing GaoLin Shen

Published in: Journal of translational medicine (2018)

Our PDX models were established from real time biopsies and molecularly profiled. They might be promising for drug development and individualized therapy.

Keyphrases

ultrasound guided
copy number
dna methylation
replacement therapy
cell therapy
smoking cessation