Inhalable polymer nanoparticles for versatile mRNA delivery and mucosal vaccination.
Alexandra SuberiMolly K GrunTianyang MaoBenjamin IsraelowMelanie ReschkeJulian GrundlerLaiba AkhtarTeresa LeeKwangsoo ShinAlexandra S Piotrowski-DaspitRobert J HomerAkiko IwasakHee Won SuhW Mark SaltzmanPublished in: bioRxiv : the preprint server for biology (2022)
Inhaled polymer nanoparticles (NPs) achieve high mRNA expression in the lung and induce protective immunity against SARS-CoV-2.