Interaction between dietary branched-chain amino acids and genetic risk score on the risk of type 2 diabetes in Chinese.

Weiqi WangHaiyang JiangZiwei ZhangWei DuanTianshu HanChanghao Sun

Published in: Genes & nutrition (2021)

This study indicated that dietary BCAAs could amplify the genetic association with T2D risk and fasting glucose. Moreover, higher BCAA intake showed positive association with T2D when genetic predisposition was also high but changed to negative when genetic predisposition was low.

Keyphrases

type diabetes
genome wide
copy number
blood glucose
amino acid
cardiovascular disease
gene expression
physical activity
glycemic control
body mass index