Poly lactic-co-glycolic acid scaffold loaded with plasmid DNA encoding fibroblast growth factor-2 promotes periodontal ligament regeneration of replanted teeth.

Liming JiangZhenjiang DingShang XiaYao LiuShuang LeiMing ZhongXu Chen

Published in: Journal of periodontal research (2020)

The PLGA/pFGF-2 scaffold promoted hPDLCs proliferation and facilitated periodontal ligament-related differentiation. The PLGA/pFGF-2 scaffold possesses excellent biological characteristics and could be used as a promising biomaterial for improving the treatment prognosis of replanted tooth.

Keyphrases

tissue engineering
drug delivery
drug release
signaling pathway
cancer therapy
circulating tumor
crispr cas
wound healing
single molecule
replacement therapy