Quantitative Separation of Tremor and Ataxia in Essential Tremor.

Agostina Casamento-MoranBasma YacoubiBradley J WilkesChristopher W HessKelly D FooteMichael S OkunAparna Wagle ShuklaDavid E VaillancourtEvangelos A Christou

Published in: Annals of neurology (2020)

We demonstrate that dysmetria can be quantified independently of tremor using fast, reverse-at-target goal-directed movements. These results have important implications for the understanding of ET and other cerebellar and tremor disorders. Future research should examine the neurophysiological mechanisms underlying each symptom and characterize their independent contribution to disability. ANN NEUROL 2020;88:375-387.

Keyphrases

deep brain stimulation
parkinson disease
high resolution
current status
liquid chromatography
neural network