Pyramidal tract activation due to subthalamic deep brain stimulation in Parkinson's disease.
Philipp MahlknechtHarith AkramDejan GeorgievElina TripolitiJoseph CandelarioAndre ZachariaLudvic ZrinzoJonathan HyamMarwan HarizThomas FoltynieJohn C RothwellPatricia LimousinPublished in: Movement disorders : official journal of the Movement Disorder Society (2017)
Direct pyramidal tract activation can occur at stimulation thresholds that are within the range used in clinical routine. This spread of current compromises increase in stimulation strengths and is related to the development of side effects such as speech disturbances with chronic stimulation. © 2017 International Parkinson and Movement Disorder Society.