Microbial volatiles as diagnostic biomarkers of bacterial lung infection in mechanically ventilated patients.
Waqar M AhmedDominic FennIain R WhiteBreanna DixonTamara M E NijsenHugo H KnobelPaul BrinkmanPouline M P Van OortMarcus J SchultzPaul DarkRoyston GoodacreTimothy FeltonLieuwe D J BosStephen J Fowlernull nullPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
This study demonstrates the capability of using mVOCs to detect the presence of specific pathogen groups with potential to support clinical diagnosis. Although not all mVOCs were found in patient samples within this small pilot study, further targeted and qualitative investigation is warranted using multi-centre clinical studies.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- intensive care unit
- systematic review
- microbial community
- case report
- peritoneal dialysis
- prognostic factors
- acute respiratory distress syndrome
- risk assessment
- cancer therapy
- candida albicans
- mass spectrometry
- high resolution
- drug delivery
- human health
- extracorporeal membrane oxygenation