Binary Nanodrug-Delivery System Designed for Leukemia Therapy: Aptamer- and Transferrin-Codecorated Daunorubicin- and Luteolin-Coloaded Nanoparticles.

Yuanyuan ZhuWei ZhangJing Chen

Published in: Drug design, development and therapy (2023)

The present study showed that AP/Tf-Drn/Lut NPs are a promising drug-delivery system for targeted treatment of leukemia, due to the synergic effect of the two drugs in this system. The limitations of this system include stability during large-scale production and application from bench to bedside.

Keyphrases

acute myeloid leukemia
bone marrow
gold nanoparticles
transcription factor
cancer therapy
ionic liquid
combination therapy
replacement therapy
magnetic nanoparticles
drug induced