CTLA4-Ig Abatacept Ameliorates Proteinuria by Regulating Circulating Treg/IL-17 in Adriamycin-Induced Nephropathy Rats.

Lanjun ShuaiQia ChengTian ShenZhuwen YiXiao-Chuan Wu

Published in: BioMed research international (2020)

CTLA4-Ig abatacept can reduce proteinuria of adriamycin-induced nephropathy rats, possibly at least partially as a result of regulating circulating Treg/IL-17. CTLA4-Ig abatacept could be a promising regimen for idiopathic nephrotic syndrome.

Keyphrases

rheumatoid arthritis
high glucose
diabetic rats
drug induced
systemic lupus erythematosus
disease activity