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A phase 2 trial of consolidation pembrolizumab following concurrent chemoradiation for patients with unresectable stage III non-small cell lung cancer: Hoosier Cancer Research Network LUN 14-179.

Gregory DurmSalma K JabbourSandra K AlthouseZiyue LiuAhad A SadiqRobin T ZonShadia I JalalGoetz H KloeckerMichael J WilliamsonKaren L ReckampRobert M LangdonEbenezer A KioRyan D GentzlerBamidele A AdesunloyeWael A HarbRadhika V WallingMichael L TitzerNasser H Hanna
Published in: Cancer (2020)
Consolidation pembrolizumab after concurrent chemoradiation improves TMDD, PFS, and OS in comparison with historical controls of chemoradiation alone. Rates of grade 3 to 5 pneumonitis were similar to those reported with chemoradiation alone.
Keyphrases
  • locally advanced
  • rectal cancer
  • squamous cell carcinoma
  • radiation therapy
  • advanced non small cell lung cancer
  • papillary thyroid
  • squamous cell
  • epidermal growth factor receptor