Next-generation sequencing improves treatment efficacy and reduces hospitalization in children with drug-resistant epilepsy.

Jing PengNan PangYing WangXiao-Le WangJian ChenJuan XiongPan PengCan-Hui ZhuMiriam Barakael KessiFang HeFei Yin

Published in: CNS neuroscience & therapeutics (2018)

These results offer further proof that NGS approaches represent powerful tools for establishing a definitive diagnosis. Moreover, this study indicated how NGS can improve treatment efficacy and reduce hospitalization in children with DRE.

Keyphrases

drug resistant
multidrug resistant
gene expression
radiation therapy
replacement therapy
copy number
locally advanced