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New methods for objective angiogenesis evaluation of rat nerves using microcomputed tomography scanning and conventional photography.

Tiam M SaffariFemke MathotAllen T BishopAlexander Y Shin
Published in: Microsurgery (2019)
Both methods are considered to successfully reflect the degree of vascularization. Application of this technique could be used to visualize and objectively quantify angiogenesis of the transplanted nerve graft. Moreover, this simple method is easily reproducible and could be extrapolated to any other desired target organ ex vivo in small animals to investigate the vascular network.
Keyphrases
  • endothelial cells
  • vascular endothelial growth factor
  • electron microscopy
  • physical activity
  • wound healing
  • oxidative stress
  • high resolution
  • network analysis