Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura.
Charalampos MavridisGeorge GeorgiadisEleni D LagoudakiIordanis SkamagkasIoannis HeretisAnastasios V KoutsopoulosCharalampos MamoulakisPublished in: Case reports in urology (2020)
Bladder leiomyomas (BLs) are extremely rare benign tumors of mesenchymal origin. The exact pathophysiological mechanisms that lead to their appearance remain unclear including hormonal disorders, chromosomal abnormalities, and fetal remnants in the bladder. They usually remain asymptomatic for a long period of time. Solitary fibrous tumors (SFTs) are also rare neoplasms of mesenchymal origin with malignant potential usually affecting the pleura. The pathogenesis of SFTs remains unclear. We report the case of a 28-year-old male presenting with SFT of the pleura and synchronous BL. The patient presented with persistent cough as a sole symptom. Computed tomography (CT) of the thorax revealed a pleural mass, which was surgically removed and proved to be a SFT. At an early follow-up, abdominal CT scan revealed a bladder wall mass that proved to be a BL. This is the first report of BL with synchronous SFT of the pleura. Synchronous BLs and SFTs may be incidental, but the coexistence of two mesenchymal tumors at different sites, in a young patient, may raise the suspicion of a new clinical syndrome that warrants further investigation.
Keyphrases
- computed tomography
- case report
- spinal cord injury
- dual energy
- bone marrow
- image quality
- stem cells
- positron emission tomography
- contrast enhanced
- urinary tract
- magnetic resonance imaging
- single cell
- metabolic syndrome
- risk assessment
- gene expression
- dna methylation
- density functional theory
- adipose tissue
- copy number
- genome wide
- patient reported
- insulin resistance