Incidence and Predictors of Progression to Chagas Cardiomyopathy: Long-Term Follow-Up of Trypanosoma cruzi-Seropositive Individuals.
Maria do Carmo Pereira NunesLewis F BussJose Luiz P SilvaLarissa Natany A MartinsClaudia Di Lorenzo OliveiraClareci Silva CardosoBruno Oliveira de Figueiredo BritoAriela Mota FerreiraLea Campos OliveiraAna Luiza BierrenbachFabio FernandesMichael P BuschViviane Tiemi HottaLuiz Mário Baptista MartinelliMaria Carolina F Almeida SoeiroAdriana BrenteganiVera M C SalemiMarcia M MenezesAntonio Luiz Pinho RibeiroEster Cerdeira SabinoPublished in: Circulation (2021)
We present a comprehensive description of the natural history of T. cruzi seropositivity in a contemporary patient population. The results highlight the central importance of anti-T. cruzi antibody titer as a marker of Chagas disease activity and risk of progression.