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Age-stratified comparison of prognosis in cardiac resynchronization therapy with or without prophylactic defibrillator for non-ischemic cardiomyopathy - a nationwide cohort study.

Maiwand FarouqCecilia RorsmanSofia MarinkoDavid MörtsellUzma ChaudhryLingwei WangPyotr G PlatonovRasmus Borgquist
Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)
In this nationwide registry-based study, patients with CRT-D have better five-year survival compared to patients with CRT-P. The interaction between age and mortality reduction not consistent, but patients with CRT-D aged <60 years had the largest absolute mortality reduction.
Keyphrases
  • cardiac resynchronization therapy
  • heart failure
  • left ventricular
  • cardiovascular events
  • risk factors
  • oxidative stress
  • ischemia reperfusion injury
  • blood brain barrier
  • cerebral ischemia