Effect of RecA inactivation and detoxification systems on the evolution of ciprofloxacin resistance in Escherichia coli.

S Diaz-DiazE RecachaA García-DuqueFernando Docobo-PérezJ BlázquezAlvaro Pascual José Manuel Rodríguez-Martínez

Published in: The Journal of antimicrobial chemotherapy (2021)

After RecA inactivation, gradual exposure to ciprofloxacin reduces the evolution of resistance. After suppression of RecA and detoxification systems, sudden high exposure to ciprofloxacin reduces the evolution of resistance in E. coli.

Keyphrases

escherichia coli
pseudomonas aeruginosa
biofilm formation
staphylococcus aureus
multidrug resistant