Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma.
Da Hyun KangSung Soo JungMin-Kyung YeoDa Hye LeeGeon YooSang Yeon ChoIn-Jae OhJu-Ock KimHee Sun ParkChaeuk ChungJeong Eun LeePublished in: BMC cancer (2020)
Our findings reinforce scientific notion of Mig-6 as an oncoprotein in the context of EGFR-TKI resistant lung adenocarcinoma. We propose that targeting Mig-6 may be a promising strategy to overcome the EGFR-TKI resistance in lung cancer.