Depression as a determinant of frailty in late life.
Marcus Kiiti BorgesIvan AprahamianCarla V RomaniniFabiana M OliveiraSilvana V B MingardiNatália A LimaJuliana Francisca CecatoMarina PetrellaRichard C Oude VoshaarPublished in: Aging & mental health (2020)
Late life depression and frailty are associated in a dose-dependent manner, irrespective of the used definitions. Nonetheless, to avoid residual confounding, future research on underlying biological mechanisms should preferably be based on formal psychiatric diagnoses and objectively assessment frailty status.