A Biological Signature for Breast Ductal Carcinoma In Situ to Predict Radiotherapy Benefit and Assess Recurrence Risk.
Troy BremerPat W WhitworthRakesh PatelJess SavalaTodd BarryStephen LyleGlen LeesmanSteven P LinkeKarin JirströmWenjing ZhouRose-Marie AminiFredrik WärnbergPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)
The DS was prognostic for risk and predicted RT benefit for DCIS patients. DS identified a clinically meaningful low-risk group and a group with elevated 10-year risks that received substantial RT benefit over baseline.