Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia.

Rozana Santos TeixeiraRegina Terse-RamosTatiane Anunciação FerreiraVinícius Ramos MachadoMarya Izadora PerdizIsa Menezes LyraValma Lopes NascimentoNey Boa-SorteBruno B AndradeAna Marice Ladeia

Published in: PloS one (2017)

Children and adolescents with SCA exhibit impaired endothelial function. Reductions in FMD values are associated with ACS. These findings underline the potential use of FMD as screening strategy of SCA patients with severe prognosis at early stages.

Keyphrases

acute coronary syndrome
chronic kidney disease
early onset
iron deficiency
risk assessment
drug induced