Effect of COX-2 inhibition on tendon-to-bone healing and PGE2 concentration after anterior cruciate ligament reconstruction.
Martin SauerschnigJosef Stolberg-StolbergCarmen SchmidtValerie WienerroitherMichael PleckoKarin SchlichtingCarsten PerkaChristian DynybilPublished in: European journal of medical research (2018)
Selective COX-2 inhibitors cause impaired tendon-to-bone healing, weaken mechanical stability and decrease PGE2 content of the synovial fluid. The present study suggests a reluctant use of COX-2 inhibitors when tendon-to-bone healing is intended.