Collagen proportionate area correlates with histological stage and predicts clinical events in primary sclerosing cholangitis.
Francesca SaffiotiAndrew HallManon de KrijgerJoanne VerheijStefan G HübscherJames MauriceTu Vinh LuongMassimo PinzaniCyriel Y PonsioenDouglas ThorburnPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Quantitative fibrosis assessment by CPA has utility in PSC. It correlates with established histological staging systems and predicts clinical events. CPA may be a useful tool for staging fibrosis and for risk stratification in PSC and should be evaluated further within prospective clinical trials.