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miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway.

Li JiaShihua LuoXiang RenYang LiJialei HuBing LiuLifen ZhaoYujia ShanHuimin Zhou
Published in: Digestive diseases and sciences (2017)
The miR-182/-135b/ST6GALNAC2/PI3K/AKT axis may serve as a predictive biomarker and a potential therapeutic target in CRC treatment.
Keyphrases
  • pi k akt
  • cell proliferation
  • signaling pathway
  • cell cycle arrest
  • long non coding rna
  • cancer therapy
  • human health
  • risk assessment
  • climate change