Potential Candidate Genes for Therapeutic Targeting in Chronic Myeloid Leukemia: A Pilot Study.

Khaldoon AlsammanAli M AlamriChittibabu VatteAmani Y OwaidahFatimah AlhassanRoba MubarkiOmar S El-Masry

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

This study highlights RPL9, RPL34, RPL36A, RPL39, CCDC170, LDB1, and SBF1 as potential targets in CML. Additionally, it underscores the importance of investigating these genes and their variants in larger cohort studies to assess their clinical significance in CML patients.

Keyphrases

chronic myeloid leukemia
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
human health
peritoneal dialysis
gene expression
copy number
risk assessment
patient reported outcomes
cancer therapy
dna methylation
genome wide analysis