Anti-Zika virus activity and chemical characterization by ultra-high performance liquid chromatography (UPLC-DAD-UV-MS) of ethanol extracts in Tecoma species.
Adriana Cotta Cardoso ReisBreno Mello SilvaHélia Maria Marques de MouraGuilherme Rocha PereiraGeraldo Célio BrandãoPublished in: BMC complementary medicine and therapies (2020)
The Tecoma species demonstrated interesting in vitro activity against the Zika virus. The crenatoside, phenylethanoid glycoside that was for the first time isolated from Tecoma stans var. stans, exhibited a potent and relevant anti-Zika virus activity, being more active than ribavirin (positive control). The data show that crenatoside, was a promising compound with in vitro antiviral activity against the Zika virus.