Systematic review and meta-analysis to determine the impact of iron depletion in dysmetabolic iron overload syndrome and non-alcoholic fatty liver disease.

Arvind R MuraliAshutosh GuptaKyle Brown

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2017)

Phlebotomy does not bring about significant improvement in indices of insulin resistance, liver enzymes, or liver histology in patients with DIOS and/or NAFLD compared to lifestyle changes alone. Current evidence does not support the use of phlebotomy in patients with DIOS or NAFLD.

Keyphrases

insulin resistance
metabolic syndrome
iron deficiency
type diabetes
adipose tissue
physical activity
weight loss
polycystic ovary syndrome
skeletal muscle
glycemic control