Safety and efficacy of IDegLira titrated once weekly versus twice weekly in patients with type 2 diabetes uncontrolled on oral antidiabetic drugs: DUAL VI randomized clinical trial.

Stewart B HarrisGyőző KocsisRudolf PragerTerry RidgeKeval ChandaranaNatalie HalladinSerge Jabbour

Published in: Diabetes, obesity & metabolism (2017)

A pragmatic titration algorithm with once-weekly adjustments based on 2 PG readings resulted in a safety and glycaemic efficacy profile similar to that with twice-weekly adjustments based on 3 preceding PG values in insulin-naïve patients.

Keyphrases

type diabetes
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
clinical trial
patient reported outcomes
metabolic syndrome
insulin resistance
drug induced
double blind
weight loss