Massively parallel mutant selection identifies genetic determinants of Pseudomonas aeruginosa colonization of Drosophila melanogaster .

Jessica Miles Gabriel L Lozano Jeyaprakash RajendhranEric V StabbJo Handelsman Nichole A Broderick

Published in: bioRxiv : the preprint server for biology (2023)

establishment in its host, some of which are required across fly and mouse systems. These findings demonstrate the utility of massively parallel mutant analysis and provide a platform for aligning the fly toolkit with comprehensive bacterial genomics.

Keyphrases

drosophila melanogaster
pseudomonas aeruginosa
genome wide
wild type
cystic fibrosis
high throughput
biofilm formation
acinetobacter baumannii
dna methylation
copy number
gene expression
escherichia coli
drug resistant