Aralia taibaiensis Protects against I/R-Induced Brain Cell Injury through the Akt/SIRT1/FOXO3a Pathway.
Jialin DuanJia CuiHongnan ZhengMiaomiao XiChao GuoYan WengYing YinGuo WeiJinyi CaoYanhua WangAidong WenBoling QiaoPublished in: Oxidative medicine and cellular longevity (2019)
sAT protected brain cells from I/R-induced mitochondrial oxidative stress and dysfunction through regulating the Akt/SIRT1/FOXO3a/PGC-1α pathway.
Keyphrases
- oxidative stress
- diabetic rats
- signaling pathway
- high glucose
- ischemia reperfusion injury
- cell proliferation
- transcription factor
- dna damage
- white matter
- resting state
- pi k akt
- induced apoptosis
- skeletal muscle
- drug induced
- functional connectivity
- cerebral ischemia
- cell therapy
- mesenchymal stem cells
- endoplasmic reticulum stress
- blood brain barrier