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Genetic resiliency and the Black Death: No apparent loss of mitogenomic diversity due to the Black Death in medieval London and Denmark.

Jennifer KlunkAna T DugganRebecca RedfernJulia GambleJesper L BoldsenG Brian GoldingBrittany S WalterKatherine EatonJulianna StangroomJean-Marie RouillardAlison DevaultSharon N DeWitteHendrik N Poinar
Published in: American journal of physical anthropology (2019)
The mitochondrial genomes of both medieval Londoners and medieval Danes suggest high mitochondrial diversity before, during and after the Black Death. While our mitochondrial genomic data lack geographically correlated signals, these data could be the result of high, continual female migration before and after the Black Death or may simply indicate a large female effective population size unaffected by the upheaval of the medieval period. Either scenario suggests a genetic resiliency in areas of northwestern medieval Europe.
Keyphrases
  • oxidative stress
  • electronic health record
  • copy number
  • genome wide
  • big data
  • magnetic resonance imaging
  • computed tomography
  • deep learning
  • data analysis
  • diffusion weighted imaging