Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.

Joshua J MifflinLoren E DupuisNicolas E AlcalaLea G RussellChristine B Kern

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2018)

Intercalated cushions of the developing outflow tract are populated with Tnnt2-Cre derived cells, a Cre reporter previously used for tracing and excision of myocardial cells and not previously associated with mesenchymal cells. Developmental Dynamics 247:1005-1017, 2018. © 2018 Wiley Periodicals, Inc.

Keyphrases

induced apoptosis
cell cycle arrest
left ventricular
endoplasmic reticulum stress
stem cells
heart failure
cell death
signaling pathway
bone marrow
atrial fibrillation