Visible light photoredox-catalyzed arylative cyclization to access benzimidazo[2,1- a ]isoquinolin-6(5 H )-ones.

A photoredox-catalyzed arylative radical cascade involving N -acryloyl-2-arylbenzoimidazoles and diaryliodonium triflates leading to the formation of a broad array of pharmaceutically important arylated-benzimidazo[2,1- a ]isoquinolin-6(5 H )-ones is described. Importantly, the synthesized benzimidazoisoquinolinones are amenable for further synthetic manipulation and allowed efficient access to benzimidazo-fused polycyclic heterocycles.