Tmem2 restricts atrioventricular canal differentiation by regulating degradation of hyaluronic acid.

Lydia HernandezLucile RyckebüschCarole WangRachel LingDeborah Yelon

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)

Taken together, our data support a model in which HA degradation, regulated by Tmem2, limits the distribution of Wnt signaling and thereby confines the differentiation of the AVC.

Keyphrases

hyaluronic acid
electronic health record
big data
atrial fibrillation
deep learning