Login / Signup

Evaluation of doravirine-based regimen population target in a large Italian clinical center.

Damiano FarinacciArturo CicculloFrancesca LombardiDavide MoscheseAnna D'AngelilloValentina IannoneFrancesco LamannaRosa Anna PasserottoSimona Di Giambenedetto
Published in: Antiviral therapy (2021)
DOR represents a good option for switch strategies in virological suppressed PLWHIV. It seems to have a higher genetic barrier and a lower risk for resistance mutation development compared to other NNRTI. In our cohort, we found 81.8% of patients who could be eligible for a regimen containing DOR and almost 2/3 of patients who can be treated with the fixed-dose combination DOR/3TC/TDF.
Keyphrases
  • hiv infected
  • genome wide
  • antiretroviral therapy
  • hiv infected patients
  • copy number
  • gene expression
  • newly diagnosed