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Genomic alterations in biliary tract cancer predict prognosis and immunotherapy outcomes.

Xiaofeng ChenDeqiang WangJing LiuJingrong QiuJun ZhouJieer YingYan ShiZhaoxia WangHaizhou LouJiuwei CuiJingdong ZhangYunpeng LiuFengjiao ZhaoLanlan PanJianyi ZhaoDongqin ZhuShiqing ChenXiangcheng LiXue LiLiuqing ZhuYang ShaoYongqian Shu
Published in: Journal for immunotherapy of cancer (2022)
Genomic alterations in advanced BTC were associated with specific prognosis and immunotherapy outcomes. Combining genomic classification with TME evaluation further improved the stratification of immunotherapy outcomes.
Keyphrases
  • copy number
  • machine learning
  • squamous cell carcinoma
  • papillary thyroid
  • deep learning
  • gene expression
  • adipose tissue
  • dna methylation
  • skeletal muscle
  • squamous cell
  • lymph node metastasis
  • weight loss