Keratinocyte-derived circulating microRNAs in extracellular vesicles: a novel biomarker of psoriasis severity and potential therapeutic target.

Young Joon ParkDong Chan KimSoo-Jin LeeHan Seul KimJi Young PakJunho KimJae Youn CheongEun So Lee

Published in: Journal of translational medicine (2024)

We propose keratinocyte-derived EV miR-625-3p as a novel and reliable biomarker for estimating the severity of psoriasis. This biomarker could objectively evaluate the severity of psoriasis in the clinical setting and might serve as a potential therapeutic target. Trial registration None.

Keyphrases

clinical trial
physical activity
human health
phase iii
risk assessment
phase ii
climate change
open label