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The modulation of autophagy and unfolded protein response by ent-kaurenoid derivative CPUK02 in human colorectal cancer cells.

Sedigheh RezayiMorvarid SiriNasim Rahmani-KukiaMozhdeh ZamaniSanaz DastghaibPooneh Mokarram
Published in: Molecular biology reports (2024)
The study findings suggest CPUK02 may exert its cytotoxic effects by inhibiting UPR and autophagy flux in colorectal cancer cells.
Keyphrases
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • endothelial cells
  • oxidative stress
  • protein protein