Intratumoral genetic heterogeneity and number of cytogenetic aberrations provide additional prognostic significance in chronic lymphocytic leukemia.
Shuhua YiZengjun LiDehui ZouGang AnShizhen ZhongHeng LiWenjie XiongChenwen LiWeiwei ChenWei LiuRui LvZhen YuHuijun WangYan XuKeshu ZhouKun RuJianxiang WangTao ChengLugui QiuPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2016)
The number of cytogenetic aberrations and the size of intratumoral genetic subclones should be comprehensively considered to determine the prognosis for CLL.Genet Med 19 2, 182-191.