Overcorrection and Undercorrection with Fixed Dosing of Bolus Hypertonic Saline for Symptomatic Hyponatremia.
Anissa PeloutoJulie C RefardtMirjam Christ-CrainAdrienne A M ZandbergenEwout J HoornPublished in: European journal of endocrinology (2023)
Our real-world data suggest that fixed dosing of bolus hypertonic saline may expose patients with low and high body weight to more overcorrection and undercorrection, respectively. Prospective studies are needed to develop and validate individualized dosing models.