Glycosylation of anthocyanins enhances the apoptosis of colon cancer cells by handicapping energy metabolism.

Nan JingJiaxing SongZheng LiuLuoyang WangGuoqiang Jiang

Published in: BMC complementary medicine and therapies (2020)

The study suggested that the glycosides of anthocyanins might handicap glucose transport and inhibit energy metabolism, which, in turn, led to mitochondrial damage and apoptosis of tumour cells.

Keyphrases

cell cycle arrest
oxidative stress
induced apoptosis
cell death
endoplasmic reticulum stress
pi k akt
signaling pathway
blood glucose
cell proliferation
adipose tissue
living cells
skeletal muscle