The Shapiro-Procalcitonin algorithm (SPA) as a decision tool for blood culture sampling: validation in a prospective cohort study.

Géraldine WyssSilvia BergerSebastian HaubitzHans FankhauserUlrich BuergiBeat MuellerPhilipp SchuetzChristoph A FuxAnna Conen

Published in: Infection (2020)

This study validates the high predictive value of SPA for bacteremia, increasing true BC positivity from 15 to 26%. Restricting BC sampling to SPA would have reduced BC sampling by 48%, while still detecting 194/215 organisms (90%), which makes SPA a valuable diagnostic stewardship tool.

Keyphrases

gram negative
machine learning
deep learning
decision making
neural network
acute care
clinical evaluation