Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury.

Ling GaoYichao ZhaoHaiyan Wu Xian-Hua LinFei GuoJie LiYuhang LongBokang ZhouJunsen SheChen ZhangJianzhong ShengLi JinYanting WuHe-Feng Huang

Published in: Circulation (2023)

Our data documented previously unrecognized mechanisms through which PCOS could affect cardiovascular health in women. PCOS may promote myocardial macrophage accumulation and post-MI cardiac remodeling because of augmented splenic myelopoiesis.

Keyphrases

polycystic ovary syndrome
left ventricular
insulin resistance
adipose tissue
oxidative stress
electronic health record
type diabetes
metabolic syndrome
skeletal muscle
big data
pregnant women
blood brain barrier