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Re-Evaluate Fusion Genes in Prostate Cancer.

Ting WeiJi LuTao MaHaojie HuangJean-Pierre KocherLiguo Wang
Published in: Cancer informatics (2021)
Most of the reported fusion genes cannot be validated by TCGA samples. The ETS family and androgen response genes were significantly enriched in prostate cancer-specific fusion genes. Transcription activity was significantly repressed, and the DNA methylation was significantly increased in samples carrying ERG fusion.
Keyphrases
  • prostate cancer
  • genome wide
  • dna methylation
  • bioinformatics analysis
  • genome wide identification
  • radical prostatectomy
  • gene expression
  • genome wide analysis