Long-term pegylated growth hormone for children with growth hormone deficiency: a large, prospective, real-world study.
Ling HouKe HuangChunxiu GongFeihong LuoHaiyan WeiLiyang LiangHongwei DuJianping ZhangYan ZhongRuimin ChenXinran ChenJiayan PanXianjiang JinTing ZengWei LiaoDeyun LiuDan LanShunye ZhuZhiya DongHuamei MaYu YangFeng XiongPing Lu MbShengquan ChengXuefan GuRunming JinYu LiuJinzhun WuXu XuLinqi ChenQin DongHui PanZhe SuLijun LiuXiaoming LuoShining NiZhihong ChenYuhua HuChunlin WangJing LiuLi LiuBiao LuXinli WangYunfeng WangFan YangManyan ZhangLizhi CaoGeLi LiuHui YaoYaqin ZhangMingjuan DaiGuimei LiLi LiYanjie LiuKan WangYanfeng XiaoXingxing ZhangJunhua DongZaiyan GuLirong YingFeng HuangYanling LiuZheng LiuJin YeDongmei ZhaoXu HuZhihong JiangKan YeHong ZhuShaoke ChenXiaobo ChenNaijun WanZhuangjian XuQingjin YinHongxiao ZhangXiaodong HuangJianying YinHuifeng ZhangPin LiPing YinJun-Fen FuXiaoping LuoPublished in: The Journal of clinical endocrinology and metabolism (2023)
PEG-rhGH showed long-term effectiveness and safety in treating children with GHD. Both dose subgroups showed promising outcomes, while PEG-rhGH 0.2 mg/kg/week might show additional benefit.