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Preliminary Study of White Matter Abnormalities and Associations With the Metabotropic Glutamate Receptor 5 to Distinguish Bipolar and Major Depressive Disorders.

Siyan FanRuth H AschMargaret T DavisNicole DellaGioiaRyan CoolHilary P BlumbergIrina Esterlis
Published in: Chronic stress (Thousand Oaks, Calif.) (2024)
These novel preliminary findings suggest important associations between lower UF FA and lower amygdala mGlu5 levels that could represent a disorder-specific neural mechanism in which mGluR5 is associated with the frontotemporal dysconnectivity of the disorder.
Keyphrases
  • white matter
  • bipolar disorder
  • functional connectivity
  • stress induced
  • multiple sclerosis
  • resting state